I did updates at 9 months, 2 years, and 3 years, but after the 3-year update I got a Fraxel Dual Laser treatment done so I wasn't going to do any more Retin-A updates. Like many other skin care products that has expired, the can still be used because the skin care products manufacturers do not put the exact date that the products actually expires but an estimated time before they think the product will expire. 3. So much so that I wrote an entire article about how to deal with the redness and flakiness. Retinoids are well known for being the ultimate does-it-all skin solution. 'Eight long-expired medications with 15 different active ingredients were discovered in a retail pharmacy in their original, unopened containers. Affiliate Disclosure: I receive a small commission for purchases made via affiliate links.. Usually expired meds are not recommended to be used as the effects of the meds are no longer guaranteed & it … I have 2 expired tubes of Differin, 1 is cream (expired 04/12), & the other is gel (expired 03/12). Retinoic-acid and it's close cousin, Accutane, are teratogenic (they kill quickly dividing cells, like chemotherapy drugs), and are toxic. I recently started using a prescription tretinoin cream, a generic version of Retin-A. Retin-A Causes Irritation and Inflammation. We all know Retin-A is irritating. I decided to start using Retin-A (tretinoin) after I turned 50, when I started seeing the visible signs of aging in the mirror every morning. Tretinoin, Retin-A etc do not contain the normal vitamin form of Vitamin-A, but rather a more uncommon form, retinoic-acid. Tretinoin is probably THE most popular and evidence-supported prescription retinoid (vitamin A derivative), and works as an acne treatment, for anti-aging, and a generous handful of other skin issues. Hi, i'm using tretinoin .05% prescribed by my doctor and at the same time benzOyl peroxide facial wash. I've been using Retin-A for 3 years now and it's time to check in with before & after pictures to see if I'm still getting good results! I started using prescription Retin-A 5 years ago when I turned 50. Although their are mixed answers whether or not expired Retin A can still be used. With the right regimen and application strategies, some people, usually with hardier skin types, find a way to manage it. In today's post, I'm doing a 5-Year Retin-A Update showing results on wrinkles in Before & After photos. All had expired 28 to 40 years prior to analysis...In our data set, 12 of 14 medications retained full potency for at least 336 months, and 8 of these for at least 480 months.' Asked 3 Jun 2010 by palmdalegirl Updated 3 June 2010 Topics tretinoin If it doesn’t have a symbol, it may have been on the original packaging, which is likely discarded. 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